36^th Global Summit on Pediatrics February 23-24, 2022 Tokyo, Japan

Biography:

As a nurse, my first exposure was labor room to contact with a newborn which motivate me to become a child nurse. Child nursing is a very challenging and demanding career, however, as nurse researchers; it is our responsibility to add new knowledge to the pediatric field. Doing research in nursing has always been a desire for me so I constantly struggle to upgrade my knowledge through nursing education.

Abstract:

As a nurse, my first exposure was labor room to contact with a newborn which motivate me to become a child nurse. Child nursing is a very challenging and demanding career, however, as nurse researchers; it is our responsibility to add new knowledge to the pediatric field. Doing research in nursing has always been a desire for me so I constantly struggle to upgrade my knowledge through nursing education.

Biography:

Debre Tabor University - Department of Pediatric and Child Health Nursing, Debre Tabor University - College of Health Sciences, Debre Tabor University - College of Health Sciences, Department of Emergency and Critical Care Nursing, College of Health Sciences, Debre Tabor University, Department of Pediatric and Child Health Nursing, College of Health Sciences, Debre Tabor University and Department of Pediatric and Child Health Nursing, College of Health Sciences, Debre Tabor University

Abstract:

Introduction- Burn is a severe type of traumatic injury, which can lead to deformity, disability, or death, and remains a significant health problem worldwide. It is one of the leading causes of morbidity and mortality among Ethiopian children, as many hospitals are lacking a well-equipped and prepared burn center. Children under the age of 15 are at increased risk of burn related complications. Because they may not be able to escape from the burning object, they often experience a long duration of contact with the hot substance, with a resultant deep burn injury and death.

Methods- Institutional-cross sectional study was used to study 375 hospitalized burn injury survivor pediatrics’ from 2015 to 2019. A simple random sampling method was used to select participants. Data were exported from Epidata version 4.6 to SPSS version 25 for analysis. In multivariable analysis significant of the variables were considered at p-value of ≤ 0.05. 

Result- In total, 353 were included in the study. Of 353 burn injury survivors, the prevalence of pathological scar was 125(35.4%). In multivariable analysis, depth of burn injury, time since burn injury, a patient who have a referred to physiotherapy by the surgeon, and surgical procedure is done after burn were statistically significant with a complication of burn injury survivors.  

Conclusion and Recommendation- This study revealed that the burden of pathological scar among survivors of burn injury was unacceptably high, which needs intervention from the concerned bodies. Since this high burden of complication might result from the limitation of applying Interburn recommendation the Amhara regional health bureau and the South Gondar health department shall work in collaboration with Interburn to provide Essential burn care and advanced burn care training for health care providers. The timely intervention of those who have a second and third-degree burn, promoting early presentation to hospital, providing appropriate physiotherapy, and proper care for those who have surgical intervention may help to decrease pathological scar for burn victim children.

Biography:

Dr. Firaol Dandena is an Ethiopian medical doctor. He received his medical doctorate degree from Saint Paul Hospital Millennium Medical College. He is a research coordinator for the CURE network, as well as a quality and patient safety manager at the CURE children's hospital in Ethiopia. His work focuses on improving surgical care, quality improvement, and patient safety, as well as assessing and developing a mitigation plan for COVID 19's effect on health care. He is currently working on a number of research topics and has three publications in internationally reputable journals.

Abstract:

Dr. Firaol Dandena is an Ethiopian medical doctor. He received his medical doctorate degree from Saint Paul Hospital Millennium Medical College. He is a research coordinator for the CURE network, as well as a quality and patient safety manager at the CURE children's hospital in Ethiopia. His work focuses on improving surgical care, quality improvement, and patient safety, as well as assessing and developing a mitigation plan for COVID 19's effect on health care. He is currently working on a number of research topics and has three publications in internationally reputable journals.

Biography:

Lubogo Patrick completed his Bachelor of Pharmacy in 2017 from Makerere University, Uganda and Master of Pharmacy in Clinical Pharmacy at Mbarara University of Science and technology, Uganda. He is a lecturer of Clinical Pharmacy at Kampala International University and his research interest lies in the area of Pharmacoeconomics and Outcome Research.

Abstract:

Background: Malaria, pneumonia and diarrhoea continue to be the leading causes of death in children under the age of five years (U5) in Uganda. To combat these febrile illnesses, integrated community case management (iCCM) delivery models utilizing community health workers (CHWs) or drug sellers have been implemented. The purpose of this study is to compare the cost effectiveness of delivering iCCM interventions via drug sellers versus CHWs in rural Uganda Methods: This study was a cost-effectiveness analysis to compare the iCCM delivery model utilizing drug sellers against the model using CHWs. The effect measure was the number of appropriately treated U5 children, and data on effectiveness came from a quasi-experimental study in Southwestern Uganda and the inSCALE cross-sectional household survey in eight districts of mid-Western Uganda. The iCCM interventions were costed using the micro-costing (ingredients) approach, with costs expressed in US dollars. Cost and effect data were linked together using a decision tree model and analysed using the Amua modelling software.

Biography:

Raffaele Pilla, Pharm.D., Ph.D., Doctor Europaeus, received his Master’s degree in Pharmacy at G. d’Annunzio University in Chieti-Pescara, Italy in 2005, where he also served internships at the Cell Physiology Laboratory and Molecular Biology Laboratory. Prior, he was an Erasmus Student at Faculté de Pharmacie de Reims in Reims, France. He received his Doctor Europaeus in 2010 from Pitié-Salpétrière Institute in Paris, France. Also in 2010, he received his Ph.D. in Biochemistry, Physiology, and Pathology of Muscle at G. d’Annunzio University in Chieti-Pescara, Italy. He was hired as a Postdoctoral Scholar in the Department of Pharmacology and Physiology at the University of South Florida in Tampa, on two research grants funded by the Office of Naval Research (US Navy) and Divers’ Alert Network. He has written and lectured widely worldwide. He has been involved in ongoing research at the University of South Florida with the use of ketone esters.

Abstract:

It has been recently shown that nutritional ketosis is effective against seizure disorders and various acute/chronic neurological disorders. Physiologically, glucose is the primary metabolic fuel for cells. However, many neurodegenerative disorders have been associated with impaired glucose transport/metabolism and with mitochondrial dysfunction, such as Alzheimer’s/Parkinson’s disease, general seizure disorders, and traumatic brain injury. Ketone bodies and tricarboxylic acid cycle intermediates represent alternative fuels for the brain and can bypass the ratelimiting steps associated with impaired neuronal glucose metabolism. Therefore, therapeutic ketosis can be considered as a metabolic therapy by providing alternative energy substrates. It has been estimated that the brain derives over 60% of its total energy from ketones when glucose availability is limited. In fact, after prolonged periods of fasting or ketogenic diet (KD), the body utilizes energy obtained from free fatty acids (FFAs) released from adipose tissue. Because the brain is unable to derive significant energy from FFAs, hepatic ketogenesis converts FFAs into ketone bodies-hydroxybutyrate (BHB) and acetoacetate (AcAc)-while a percentage of AcAc spontaneously decarboxylates to acetone. Large quantities of ketone bodies accumulate in the blood through this mechanism. This represents a state of normal physiological ketosis and can be therapeutic. Ketone bodies are transported across the blood-brain barrier by monocarboxylic acid transporters to fuel brain function. Starvation or nutritional ketosis is an essential survival mechanism that ensures metabolic flexibility during prolonged fasting or lack of carbohydrate ingestion. Therapeutic ketosis leads to metabolic adaptations that may improve brain metabolism, restore mitochondrial ATP production, decrease reactive oxygen species production, reduce inflammation, and increase neurotrophic factors’ function. It has been shown that KD mimics the effects of fasting and the lack of glucose/insulin signaling, promoting a metabolic shift towards fatty acid utilization. In this work, the author reports a number of successful case reports treated through metabolic ketosis.